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[1]张帆,马翔,姜杰,等.异丙醇与丙酸酐酯化反应的安全控制条件[J].中国安全生产科学技术,2013,9(9):11-14.[doi:10.11731/j.issn.1673-193x.2013.09.002]
　ZHANG Fan,MA Xiang,JIANG Jie,et al.Safetycontrol conditions in esterification of isopropyl alcohol and propionic anhydride[J].JOURNAL OF SAFETY SCIENCE AND TECHNOLOGY,2013,9(9):11-14.[doi:10.11731/j.issn.1673-193x.2013.09.002]
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异丙醇与丙酸酐酯化反应的安全控制条件
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《中国安全生产科学技术》[ISSN:1673-193X/CN:11-5335/TB]

卷:
9
期数:
2013年9期
页码:
11-14
栏目:
学术论著
出版日期:
2013-09-30

文章信息/Info

Title:
Safetycontrol conditions in esterification of isopropyl alcohol and propionic anhydride
作者:
张帆1; 2; 马翔1; 2; 姜杰2; 谢传欣2
（1.青岛科技大学化工学院，山东青岛266042；2.中国石油化工股份有限公司青岛安全工程研究院， 化学品安全控制国家重点实验室，山东青岛266071）
Author(s):
ZHANG Fan 1; 2 ; MA Xiang 1; 2 ; JIANG Jie 2;  XIE Chuan xin 2
(1.College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao Shandong 266042, China； 2. SINOPEC Safety Engineering Institute, State Key Laboratory of Safety and Control for Chemicals，Qingdao Shandong 266071， China)
关键词:
丙酸异丙酯; 反应动力学; 反应失控; 优化
Keywords:
Isopropyl propionate; reaction kinetics; runaway reaction; optimization
分类号:
X937
DOI:
10.11731/j.issn.1673-193x.2013.09.002
文献标志码:
A
摘要:
针对异丙醇与丙酸酐酯化合成丙酸异丙酯工艺的反应失控危险性，利用泄放尺寸实验仪（VSP2）研究了其反应的放热特性，选择自催化模式模拟得到了反应动力学参数，并与实验数据进行了对比验证；利用得到动力学模型，模拟了该工艺在半间歇模式、反应温度为70℃时，中试规模（＞100L）条件下的反应特点，分析了反应失控的危险性，并针对加料程序进行了优化设计，得到最佳控制方法
Abstract:
Vent size Package 2 (VSP2) was used to analyze the thermal behavior in synthesis reaction of isopropyl propionate, The reaction kinetics were simulated with autocatalytic model, and validated by experimentations. The reaction characteristics were simulated in semibatch mode, with the reaction temperature of 70℃，pilotscale (100L). The hazards of runaway reaction were discussed, and the feed program was optimized.

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备注/Memo

备注/Memo:
国家“十二五”科技支撑计划课题（2012BAK13B02）
更新日期/Last Update: 2013-09-30