|本期目录/Table of Contents|

[1]李永兴,李建波,李运才,等.剧毒化学品甲苯-2，4-二异氰酸酯运输危险性评估[J].中国安全生产科学技术,2009,5(5):97-101.
　LI Yong xing,LI Jian bo,LI Yun cai,et al.The hazard assessment during the transportation of toluene-2,4-diisocyanate as a high toxicity chemical[J].JOURNAL OF SAFETY SCIENCE AND TECHNOLOGY,2009,5(5):97-101.
点击复制

剧毒化学品甲苯-2，4-二异氰酸酯运输危险性评估()
分享到：

《中国安全生产科学技术》[ISSN:1673-193X/CN:11-5335/TB]

卷:
5
期数:
2009年5
页码:
97-101
栏目:
出版日期:
2009-10-31

文章信息/Info

Title:
The hazard assessment during the transportation of toluene-2,4-diisocyanate as a high toxicity chemical
文章编号:
1673-193X(2009)-05-0097-05
作者:
李永兴1; 李建波2; 李运才1; 郭秀云1
1.国家安全生产监督管理总局化学品登记中心2.中国聚氨酯工业协会异氰酸酯专业委员会
Author(s):
LI Yongxing1;  LI Jianbo2;  LI Yuncai1;  GUO Xiuyun1
1.National Registration Center for Chemicals,SAWS2.China Polyurethane Industry Association Isocyanate Subassociation
关键词:
剧毒化学品; 甲苯-2; 4-二异氰酸酯; 运输危险性
Keywords:
high toxicity chemical;  toluene-2; 4-diisocyanate; transportation hazard
分类号:
X913
DOI:
-
文献标志码:
A
摘要:
为探讨低挥发性剧毒化学品甲苯-2，4-二异氰酸酯在运输过程中大量泄漏引起群体中毒事故的可能性以及对环境的影响，对本品的急性毒性、扩散模型、环境转归、生态毒性，以及运输泄漏事故资料进行综合分析和评估。评估结果本品吸入中毒的潜在危险性指数为低度危险物质；扩散模型运输泄漏模拟危险区域下风向距离小于某些非剧毒品；环境转归研究显示本品在环境介质中没有持久性，没有明显的生物蓄积性，生态毒性较低；历年来运输泄漏事故分析未见发生大规模严重群体中毒和环境污染事故。认为本品在运输过程中大量泄漏，不会大范围扩散引起严重群体中毒事故，也不会对环境造成严重和长期的危害，建议在运输环节中运输条件适当放宽，按照一般有毒品进行管理。
Abstract:
In order to study the possibility of poisoning in population due to a spill of toluene-2,4-diisocyanate (2,4-TDI) as a high toxicity lowvolatile chemicals during transportation and its effect on environment, the acute toxicity, diffusion model, fate in environment, ecotoxicity, and accidents during transportation of 2,4-TDI were integrately analysed and assessed to provide the agents for transportation of high toxicity chemicals with references. The study concluded that the index of potential inhalation toxicity (IPIT) of 2,4-TDI showed a low hazardous substance (Class Ⅳ), that the size of hazardous zone in downwind direction modeled in a diffuse model was lower than that of nonhigh toxicity products. The fate in environment did not indicate any persistent in environment and obvious bioaccumulative. It also showed low biotoxicity. Any large scale severe poisoning in population and any environment pollution were not found in accidents during transportation in past years, Therefore it was thought that the spill of 2,4-TDIs during transportation would not lead to any severe poisoning in population due to diffuse in wide scope and to any sever longtime environment hazard. It was suggested that the conditions during 2,4-TDI transportation should be properly released and it should be taken as a common toxicity substance.

参考文献/References:

［1］何凤生.中华职业医学.北京：人民卫生出版社，1999.7［2］金泰廙.职业卫生与职业医学（第5版）.北京：人民卫生出版社，2006.230［3］World Health Organization.In International Programme on Chemical Safety. Environmental Health Criteria(EHC)75—Toluene Diisocyanates（28，1987）［4］Doe, J.E.; Horspool, G.M. Toluene DiIsocyanate:Acute Inhalation Toxicity in the Rat.III Report No. 10142. ICI Central Toxicology Laboratory,Maccles. eld, UK(1980)［5］刚葆琪.实用工业卫生工作手册.北京：人民卫生出版社，1990.277［6］王樟龄，付贵生，夏龙君.有毒气体和蒸气泄漏事故的危险度预测.化工劳动保护（工业卫生与职业病分册），1995，16（6）：261［7］马洪年.化学物质危险源的识别和评价.职业卫生与应急救援，1996，14（2）：2［8］USEPA.Aloha Download［EB/OL］.(20070515).http:www.epa.gov/ceppo/cameo/alha.htm［9］EPA550B99009.Risk Management Program Guidance for Offsite Consequence Analysis(April1999).http://www.epa.gov/emergencies/content/rmp/rmp_guidance.htm#OCA.PDF［10］Dennis C Allport,David S Gilbert,Susan M Outterside.MDI and TDI Safety， Health and the Environment.A Source Book and Practical Guide.John Wiley ＆Sons Ltd.,2002［11］Yakabe, Y., Henderson, K.M., Thompson, W.C., Pemberton, D., Tury, B. and Bailey, R.E. Fate of Methylenediphenyl Diisocyanate and Toluene Diisocyanate in the Aquatic Environment. Environ.Sci.Technol.,1999,33(15):2579［12］Sendijarevic, V. Hydrolytic stability of toluene diisocyanate and polymeric methylenediphenyl diisocyanate based polyureas under environmental conditions. Environ Sci Technol. 2004，38(4):1066～72［13］Becker KH，Bastian V，Klein T.The Reactions of OH Radicals with Toluene Diisocyanate, Toluenediamine and Methylene Dianiline under Simulated Atmospheric Conditions.J.Photochem. Photobiol., A:Chem. 1988,45：195［14］The Government of Canada Challenge for chemical substances that are a high priority for action.Chemical Substances in Batch 1 of the Challenge:Screening Assessment for TDIs(CAS RN 26471625, CAS RN 584849, CAS RN 91087)［15］Stockholm Convention on Persistent Organic Pollutants:Annex D Information Requirements and Screening Criteria［16］ESIS(European chemical Substances Information System).IUCLD DS:Existing Chemical Substance ID:26471625［17］United Nations.Globally Harmonized System of Classification and Labelling of Chemicals(GHS)（Rev.1，2005）

相似文献/References:

备注/Memo

备注/Memo:
收稿日期：2009-06-15
更新日期/Last Update: